国家自然科学基金81573206、31270030;协和青年基金3332015149;云南省应用基础研究重点项目2016FA034;云南省妇科肿瘤内设研究机构中心2014NS032;中国医学科学院病原生物学研究所基本科研业务费项目2012IPB107National Natural Science Foundation of China81573206 ,31270030;Fundamental Research Fund for the Central Universities and the PUMC Youth Fund3332015149;Applied Basic Research Project of Yunnan Province2016FA034;Foundation Program of Yunnan Province2014NS032;Fundamental Research Fund for the Institute of Pathogen Biology ,Chinese Academy of Medical Sciences & Peking Union Medical College2012IPB107