国家自然科学基金重点国际合作研究项目81620108010;国家自然科学基金面上项目81371386;中山大学临床医学研究5010计划2010003;广东省重大神经疾病诊治研究重点实验室2014B030301035Key International Cooperation Research Projects of the National Natural Science Foundation of China81620108010;General Projects of the National Natural Science Foundation of China81371386;Clinical Medical Research of the "5010" Program of Sun Yat-sen University2010003;National Key Clinical Department and Key Discipline of Neurology,the Guangdong Provincial Key Laboratory for Diagnosis and Treatment of Major Neurological Diseases2014B030301035