中国医学科学院医学与健康科技创新工程2017-I2M-1-004、2016-I2M-3-018、2017-I2M-1-008;国家科技支撑计划2011BAI11B03;国家重点基础研究发展计划2017YFC0211703 Fund program: Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences2017-I2M-1-004, 2016-I2M-3-018, 2017-I2M-1-008;National Science and Technology Infrastructure Program2011BAI11B03;National Basic Research Program of China2017YFC0211703