国家自然科学基金项目81560001;江西省青年科学基金项目20142BAB215057;江西省科技支撑计划项目20151BBG70208;江西省教育厅青年基金项目GJJ14176;江西省卫生和计生委科技项目20161018Fund program:National Natural Science Foundation of China81560001;Jiangxi Province Science Foundation for Youths20142BAB215057;Jiangxi Province Science and Technology Infrastructure Pro-gram20151BBG70208;Youth Foundation of Educational Commission of Jiangxi Province of ChinaGJJ14176;Science and Technology Project of Health and Family Planning Commission of Jiangxi Province of China20161018