四川省卫健委课题18PJ135;南充市科技局市校合作项目18SXHZ0434;川北医学院科研发展计划项目CBY17-A-YB07;A Science and Technology Project of the Sichuan Health Commission18PJ135;A School Cooperation Project of Nanchong′s Bureau of Science & Technology18SXHZ0434;The Scientific Research and Development Program of North Sichuan Medical CollegeCBY17-A-YB07