国家重点研发计划"生殖健康及重大出生缺陷防控研究"重点专项2016YFC1000204-2;国家自然科学基金81761128034;Key Special Project "Reproductive Health, Prevention and Control of Major Birth Defects" of National Key Research and Development Program2016YFC1000204-2;National Natural Science Foundation of China81761128034