国家重点研发计划2017YFC0907504;新加坡卫生部NMRC/CSA/0055/2013;美国国立卫生研究院UM1 CA182876,R01 CA144034National Key Research and Development Program of China2017YFC0907504;National Medical Research Council of SingaporeNMRC/CSA/0055/2013;National Institutes of Health,United StatesUM1 CA182876,R01 CA144034