国家自然科学基金81872631,81472991;安徽省高校优秀青年人才基金重点项目gxyqZD2018025;安徽省学术和技术带头人后备人选科研项目2017H141;合肥市卫生与计划生育委员会应用医学研究项目hwk2018zd002;国家级大学生创新训练项目201710366029National Natural Science Foundation of China81872631,81472991;Key Projects of Excellent Young Talents Fund in Universities of Anhui ProvincegxyqZD2018025;Public Welfare Technology Application Linkage Fund of Anhui Provincial Science and Technology Department2017H141;Applied Medicine Research Project of Hefei Municipal Health Planning Commissionhwk2018zd002;National College Student Innovation Training Program201710366029