国家重点研发计划2017YFC0907100;广东省自然科学基金2015A030313891;广州市科技创新委员会2013J4100031,2012J5100041;广州市卫生和计划生育委员会;中国香港大学教育发展研究基金;英国伯明翰大学提供的资金 National Key Research and Development Program of China2017YFC0907100;Guangdong Provincial Natural Science Foundation2015A030313891;Guangzhou Science Technology and Innovation Commission2013J4100031,2012J5100041;Guangzhou Health and Family Planning Commission;The University of Hong Kong Foundation for Educational Development and Research,Hong Kong,China;Fund of the University of Birmingham,UK