国家自然科学基金81471769;中央保健科研课题W2013BJ09;军队"十二五"重点项目BWS11J028;北京市科技新星课题Z141107001814099 Fund programs: National Natural Science Foundation of China81471769;Central Health Research ProjectW2013BJ09;Chinese PLA Scientifc Foundation of the Twelve?Five ProgramBWS11J028;Beijing New?Star Plan of Science and TechnologyZ141107001814099