本文课题受广东省医学科研基金项目编号A2012687;韶关市卫生计生科研项目编号Y16014;韶关市科技计划项目编号2016ws003资助@@@@This work was supported by Scientific Research Project of the Health Department of Guangdong ProvinceA2012687;Scientific Research Project of the Health and Family Planning of Shaoguan, ChinaY16014;Science and Technology Planning Project of Shaoguan, China2016ws003