10.3321/j.issn:1001-2494.2009.13.003
香加皮中甾体类化学成分研究
目的 研究香加皮中甾体类化学成分.方法 采用各种色谱技术如反复硅胶、Sephadex LH-20、ODS等柱色谱进行分离,利用现代NMR谱学技术确定化合物的结构.结果 从中分离并鉴定了7个化合物,分别为periplocogenin(1),21-O-methyl-△5-pregnene-3β,14β,17β,21-tetraol-20-one(2),△5-pregnene-3β,16α,20(S)-triol 20-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-digitalopyranoside(3),秦岭藤苷C[△5-pregnene-3β,20(S)-diol20-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside,4],△5-pregnene-3β,20(S)-diol 20-O-β-D-glucopyranosyl-(1→6)-β-D-glucoyranosyl-(1→2)-β-D-digitalopyranoside(5),秦岭藤苷D[△5-pregnene-3β,20(S)-diol 3-O-β-D-glucopyranosyl-20-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside,6],△5-pregnene-3β,16β,20(R)-triol20-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-digitalopyranoside(7).结论 化合物1、3为新天然产物,化合物4为首次从香加皮中分离得到,化合物6为首次从杠柳属中分离得到.
杠柳、化学成分、甾体类
44
R284.1(中药学)
2009-08-05(万方平台首次上网日期,不代表论文的发表时间)
共4页
968-971