脂质体作为疫苗佐剂和给药系统的应用

摘要：

Liposomes are artificial, spherical, closed vesicles consisting of one or more lipid bilayer (s). Liposomes made from ester phospholipids have been studied extensively over the last 3 decades as artificial membrane models. Considerable interest has been generated for applications of liposomes in medicine, including their use as diagnostic reagents, as carrier vehicles in vaccine formulations, or as delivery systems for drugs,
genes, or cancer imaging agents[1]. There are now liposomal formulations of conventional drugs that have received clinical approval and many others in clinical trials that bring benefits of reduced toxicity and enhanced efficacy for the treatment of cancer and other life-threatening diseases[2].

机标关键词：脂质体、疫苗佐剂、给药系统、应用、clinical trials

所属期刊栏目：22

分类号：R392.12

在线出版日期：2006-07-31（万方平台首次上网日期，不代表论文的发表时间）

页数：共7页

页码：585-591