Contingent negative variation in the aged with memory impairment in the course of advance towards dementia
Aim To investigate the feature and general trend of the contingent negativc variation (CNV) in the aged with memory iapairment(AMI) in the course of advance towards dementia. Method CNV and Hasegawa”s dementia scale for the aged(HDS)in 69 of AMI(serving as the study group) and 22 of normal elderly subjects selected from well-matched in age(serving as the control group) were examined at first. 2-3 years later, 22 of the stuty group were examined again. The wave forms and relevant indexes of CNV were observed and analyzed. Results The results showed that the RT and the time of the PINY was longer, the amplitudes and the areas of the EW and the whole wave of the CNV decreased along with the development of the memory and cognitive dysfunction in AMI. Conclusion A significant relationship was observed between severity of cognitive dysfunction, and the reduction degree of amplitude, prolongatia of RT on CNV. The CNV could constitute a valuable clue for the study of pathophysiological brain function in the early stage of mental deterioration and useful for dynamically observing the course and degree of the cognitive dysfunction in AMI.
the aged、wave forms
8
R68;R2
2005-07-07（万方平台首次上网日期，不代表论文的发表时间）
共1页
82
