A study on levels of neuropeptide Y, neurotensin motilin and calcitonin gene-reliated peptide in plasma in patients with cerebral infarction and dinical isignificance
Objective To explore the relationship between virulent Helicobacter pylori strains infection and cerebral infarction. Method We assessed the prevalence of infection by strains bearing the cytotoxin -associated gene-A(Cag-A),a strong virulence factor ,in 83 patients with cerebral infarction and in 71 age- and sex-matched controls with similar social background. Result Prevalence of Helicobacter pylori infection was significantly higher in patients than in controls(78.3% versus 56.3%,p＜0.05),with an odds ratio of 2.8(95%CI,1.46 to 5.36) adjusted for age, sex, main stroke factors. Patients with cerebral infarction also had a higher prevalence of Cag-A-positive strains(45.8% versus 19.7%, P＜0.01),with an adjusted odds ratio of 3.43(95%CI 1.5 to 7.24).Conclusion It was suggested that chronic Helicobacter pylori infection, especially Cag-A-positive strains infection is an independent risk factor for cerebral infarction.
neuropeptide Y、cerebral infarction、Helicobacter pylori infection、odds ratio、risk factor
8
R9 ;R74
2005-07-07（万方平台首次上网日期，不代表论文的发表时间）
共1页
59
