Update on Treatment of Parkinson”s Disease

摘要：

@@Prevention The best treatment is to prevent the illness in the first place or to retard its progression. There is considerable new information about Parkinson”s disease genetics and pathophysiology that hopefully will lead to therapy in this regard, but there is still nothing definitive. The only medication for which there are some reasonable data is selegiline, a monoamine oxidase (MAO)-B inhibitor. This drug actually has a symptomatic effect since it prevents the breakdown ofdopamine in the brain. Some trials have shown a beneficial effect separate from its symptomatic effect. The situation is rather controversial, however, and in one study there was an excess of mortality. ”4”There are no supportive data for antioxidants such as vitamin E, and a trial of the neurotrophic factor GDNF was not positive.

机标关键词：neurotrophic factor、monoamine oxidase、new information、vitamin E

所属期刊栏目：8

分类号：R96;R74

在线出版日期：2005-07-07（万方平台首次上网日期，不代表论文的发表时间）

页数：共2页

页码：22-23