Structure identification of 4-amino-2-(arylamino)thiazole-5-carboxylic esters
In our previous work,we found a new method by chance for the synthesis of thiazole derivatives with diversified substitutes on 2-and 5-positions of the thiazole scaffold which was published in Chinese Chemical Letters ”2014,Vol.25 p.411”.The structures were identified by 1H NMR,13C NMR and HRMS as 2-alkoxy-4-amino-N-arylthiazole-5-carboxamides,exemplified by compound 4a (Fig.1).However,in our continuous research work,we found that the reported structure of compound 4a was not corrected.It was reconfirmed as the structure of ethyl 4-amino-2-(naphthalene-2-ylamino) thiazole-5-carboxylate (4a”,Fig.1).Herein,we described the results of the structure rectification.
27
2016-05-03（万方平台首次上网日期，不代表论文的发表时间）
302-304
