Enzymatic regioselective symthesis of vinthesis of vinyl lactose ester and its chemical polymerization
Transesterification reaction of lactose with divinyladipate in pyridine catalyzed by an alkaline protease from Bacillus subtilis at 50(C for 3 days gave 6(-O-vinyladipoyl-lactose (yield 35%). Poly(6(-O-vinyladipoyl-lactose) with Mn = 21,200, Mw = 32,900, Mw/Mn = 1.56 could be obtained by chemical polymerization. Poly(vinyl alcohol) containing lactose branch was biodegradable. After 6 days in aqueous buffer (PH 7), this alkaline protease could degrade the polymer to an Mn of ca. 2100, Mw/Mn = 2.56.
Regioselectivity、vinyl ester、lactose、alkaline protease、polymerization
13
O6 ;O63
2004-01-08(万方平台首次上网日期,不代表论文的发表时间)
共4页
416-419