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Severe acute hepatitis in children with unknown aetiology,etiology analysis and the next action

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On April 5,2022,United Kingdom(UK)reported 10 cases of severe acute hepatitis with unknown cause among children under 10 years old.The initial symptoms of these cases could date back to March 2022.A rapidly increasing number of cases lasted for a month and the growth seems to be slightly slowing down in May.As of May 27,2022,the total number of children with acute hepatitis in UK reached to 222(UKHSA,2022a).European Union and European Economic Area reported 305 cases across 17 countries and none as epidemiologically linked as of May 31,2022(ECDC-WHO,2022).The report from World Health Organiza-tion(WHO)noted that a total number of 650 cases worldwide including 38(6%)cases required transplants and 9(1%)deaths(Fig.1)(WHO,2022).The Center for Disease Control and Prevention(CDC)of United States,European Center for Disease Prevention and Control(ECDC)and WHO had issued a case-based surveillance system with a common case definition and reporting protocol.The extensive investigation for detailed clinical,laboratory,epidemiological,metabolic hereditary and environmental information is under way.However,the exact cause has not been identified at press time.

analysis、children、action、next、with、acute、aetiology、hepatitis、severe、unknown

37

TP311;R726.9;S

2023-05-16(万方平台首次上网日期,不代表论文的发表时间)

共5页

778-782

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中国病毒学

1674-0769

42-1706/Q

37

2022,37(5)

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