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HCV 6a was expanding and became the predominant subtype among blood donors between 2004 and 2019 in Guangdong,China

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Dear Editor, There were an estimated 9.4 million patients with chronic hepatitis C virus(HCV)in China,putting a considerable burden on public health(Polaris Observatory HCV Collaborators,2022).What is more,the inci-dence of HCV infection increased 14.5%every year based on data from China's National Notifiable Diseases Reporting System(Zhang et al.,2019).Approximately 75%of individuals infected with HCV develops chronic hepatitis,while long-term chronic HCV infection is the most important cause of liver fibrosis,cirrhosis,and hepatocellular carcinoma.HCV is commonly transmitted through unsafe transfusion practice,in-jection drug users(IDU),and high-risk sexual behaviors.The Chinese government has launched a series of activities to guarantee the safety of blood transfusion,and the blood banks in China constitute the largest network system that screened HCV infection in the general population across the nation.But the problem of residual transmission from blood donors still exists today(Wang et al.,2013;Du et al.,2019).Previous study showed that the overall HCV prevalence ranges from 166.56 per 100,000 in first-time donors,and 15.21 per 100,000 in repeated donors in China(Fu et al.,2019).Hence,it is of paramount importance to explore the current patterns of HCV transmission among blood donors in China.

between、blood、china、among、became、donors、expanding、guangdong、predominant、subtype

37

S;R735.37;R445.1

2023-05-16(万方平台首次上网日期,不代表论文的发表时间)

共4页

765-768

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中国病毒学

1674-0769

42-1706/Q

37

2022,37(5)

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国家重点研发计划资助 课题编号:2019YFB1406304
National Key R&D Program of China Grant No. 2019YFB1406304

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