10.3978/j.issn.1000-9604.2013.04.03
Surgical organ displacement: what is the best ”materials and methods” for proton radiotherapy?
In the mid 1940s,Robert Wilson (1) hypothesized that a highly localized deposition of energy from a proton beam could be used to increase the radiation dose to tumors while minimizing radiation to adjacent normal tissues.The depthdose distribution of a proton beam differs significantly from that of a photon beam.Protons show increasing energy deposition with penetration distance,reaching a maximumnamed the Bragg peak-near the end of the range of the proton beam.In front of the Bragg peak,the dose level is modest compared to photon beams;beyond the Bragg peak,the dose decreases to nearly zero.By choosing the appropriate proton beam energy,the depth of the Bragg peak can be adjusted to match the depth and extent of the target volume.Therefore,excellent conformality can be achieved,in contrast to conventional or intensity-modulated radiotherapy (IMRT).
proton beam、depthdose distribution、energy deposition、radiation dose、photon beams、range of
25
O4 ;O57
2013-09-09(万方平台首次上网日期,不代表论文的发表时间)
共2页
267-268