Spectrophotometric Determination of Paracetamol with Microwave Assisted Alkaline Hydrolysis

摘要：

@@ Paracetamol (N-acetyl-4-amino-phenol) is a popular analgesic and antipyretic medication that is readily absorbed after administration and has few side effects and little toxicity when used in recommended dose. After ingestion of an overdose quantity of paracetamol, the accumulation of toxic metabolites may cause severe and sometimes fatal hepatotoxicity and nephrotoxicity. So, the accurate determination of paracetamol in pharmaceutical preparations and biological fluids has appeared especially attractive. For its measurement, many me thods have been developed, such as fluorometry, electrochemical method, nuclear magnetic resonance-mass spectrometry,chromatography method, and capillary electrophoresis

机标关键词：pharmaceutical preparations、capillary electrophoresis、determination of、side effects、used in

所属期刊栏目：23

分类号：R9;TQ46

资助基金：Education Foundation of Huo Yingdong supported this study81013

在线出版日期：2007-07-26（万方平台首次上网日期，不代表论文的发表时间）

页数：共2页

页码：82-83