Tumor suppressor p53 functions as an essential antiviral molecule against Japanese encephalitis virus
Japanese encephalitis virus (JEV) is a mosquito-borne virus of the family Flaviviridae.It is the causative agent of Japanese encephalitis with approximately 50,000 infection cases and 10,000 fatal cases annually in Asia (Erlanger et al.,2009).Although liveattenuated JEV vaccine has been developed and used for human and pig vaccination,JE occurs epidemically or sporadically in some developing countries or even in vaccinated areas (Solomon,2006).
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This work was supported by the National Natural Science Foundation of China Nos.81371814 and 31302116,National Program on Key Research Project of China No.2016YFD0500400 and the Program of International S&T Cooperation No.2014DFE30140.
2017-03-21(万方平台首次上网日期,不代表论文的发表时间)
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