Recurrent CNVs on 1q21.1, 15q 13.3 and 16p 11.2: shared genetic risk factors for neurodevelopmental and neuropsychiatric disorders

摘要：

@@ In the last couple of years, the discovery and characterization of copy-number variations (CNVs) in the human genome have provided a new research tool for identifying genetic risk factors of common complex diseases, referred to as CNVs based genome-wide association studies (GWAS).As ever smaller genomic rearrangements have been discovered by high resolution GWAS, both de novo and inheritable CNVs (also referred to as microdeletion/microduplication or genomic imbalances) have emerged as an important type of genetic risk factor associated with complex diseases.

机标关键词：association studies、characterization、high resolution、complex、risk factors、human genome、research、provided、type of、de novo、based、new

所属期刊栏目：36

分类号：Q3(遗传学)

在线出版日期：2010-07-12（万方平台首次上网日期，不代表论文的发表时间）

页码：191-192