tRNA-m1A modification:a translational checkpoint for T cell expansion
As the major effector cells for protecting the host from pathogens,T cells are required to meet massive demands of proteins to expand themselves quickly upon activation.In a recent paper published in Nature Immunology,Liu et al.reported that the m1A modification of transfer RNA can promote CD4+T cell proliferation by enhancing the transla-tion efficiency of a specific group of messenger RNAs,providing a new mechanism of translational control of T cell expansion.
checkpoint、cell、expansion、modification、translational、trna-m1a
33
TP302.8;S;Q945.78
2023-05-29(万方平台首次上网日期,不代表论文的发表时间)
共2页
271-272