Crank up the volume:Osmotic stress induces WNK1 phase separation
Cell shrinkage,which occurs in a hypertonic environment,results in a rapid rebound response to restore cell volume and ion concentrations.In a recent study published in Cell,Boyd-Shiwarski et al.identify WNK1,a known homeostatic regulator of cell volume,as a molecular crowding sensor,and demonstrate how WNK1 contributes to cell volume recovery through cell shrinkage-dependent phase separation.
separation、stress、volume、phase、crank、induces、osmotic
33
P746;S;TE6
2023-05-29(万方平台首次上网日期,不代表论文的发表时间)
共2页
265-266