GLP-1 appetite control via intestinofugal neurons

摘要：

The gut hormone glucagon-like peptide-1(GLP-1)holds significant therapeutic interest for glycaemic and appetite control,but an endocrine role has been questioned,since GLP-1 is broken down rapidly in the bloodstream.A major new study by Zhang et al.,identifies that a unique neuronal population within the enteric nervous system,whose axons leave the gut wall and activate sympathetic prevertebral neurons,links intestinal GLP-1 to gastric distension and acute appetite suppression,that characterizes a gastrointestinal behavior known as the"ileal brake".

机标关键词：control、appetite、intestinofugal、neurons

所属期刊栏目：32

分类号：R563.102;TH137;TQ172.6

在线出版日期：2022-08-12（万方平台首次上网日期，不代表论文的发表时间）

页数：共2页

页码：711-712