Cytoskeleton grows p62 condensates for autophagy
p62 body,a representative selective cargo for autophagy,is known to be formed via liquid-liquid phase separation,but its spatiotemporal regulation remains largely unknown.In a recent paper published in Cell Research,Feng et al.show that branched actin filaments and Myo1D collect stochastically formed nanoscale p62 bodies and grow them into micron-scale condensate,which is prerequisite for their autophagic degradation.
autophagy、condensates、cytoskeleton、grows
32
Q445;R741;Q593.2
2022-08-09(万方平台首次上网日期,不代表论文的发表时间)
共2页
607-608