SDX on the X chromosome is required for male sex determination
Dear Editor,
Sex determination is one of the most fundamental develop-ment processes,as gender is the first and most important identity of human.In most mammals,biological sex is determined by differences in sex chromosomes,1 while the autosomes are identical in both male and female.During the past 30 years,two genetic pathways of sex determination have been revealed in mammals:the testis-determining (SRY-SOX9-FGF9) and ovary-promoting (RSPO1-WNT/β-catenin-FOXL2)pathways.
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2022-03-11(万方平台首次上网日期,不代表论文的发表时间)
共4页
99-102