ERASE:a novel nucleic-acid based antiviral mechanism
Nucleic acid-based antiviral systems,including CRISPR/Cas and RNA interference,play important roles in antiviral defense.In a paper recently published in Cell Research,Wu et al.revealed a novel nucleic acid-based antiviral mechanism against RNA viruses in mouse embryonic stem cells,which relies on the endogenous reverse transcriptase to produce viral complementary DNA and then RNase H1 to destroy the viral RNA.
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2021-12-16(万方平台首次上网日期,不代表论文的发表时间)
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1142-1143