Beyond targeted protein degradation:LD·ATTECs clear cellular lipid droplets
AuTophagy-TEthering Compounds(ATTECs)are a novel class of bifunctional molecules proposed to hijack the autophagosomal pathway for the degradation of potentially any cellular components in addition to proteins.Targeting stored fats in cells with LD·ATTECs suggests a novel approach to combating diseases implicating accumulation of lipid droplets,such as obesity,cardiovascular diseases,or cancer.
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2021-10-13(万方平台首次上网日期,不代表论文的发表时间)
共2页
945-946