Pancreatic endocrinogenesis revisited:"I have all the answers,who has the questions?"
The endocrine pancreas is composed of islets of Langerhans that are scattered throughout the gland and contain multiple hormone-producing cell types(a,β,δ,PP and ε cells);endocrine progenitors(EPs)can differentiate into these distinct lineages,but the regulation of their fate choice—especially for the low-abundance δ,PP and εcells—remains incompletely understood.In a paper published in Cell Research,Yu et al.provide a notable resource to decipher the differentiation pathways of murine and human EPs.
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2021-09-13(万方平台首次上网日期,不代表论文的发表时间)
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834-835