Young haematopoietic stem cells are picky eaters
In a recent study published in Nature,Dong et al.describe how haematopoietic stem cells(HSCs)rely on chaperone-mediated autophagy(CMA),a form of highly selective lysosomal protein degradation,as a metabolic quality control mechanism.While old HSCs have reduced CMA activity,re-activation of CMA can boost their functionality,providing exciting therapeutic perspectives.
31
2021-05-31(万方平台首次上网日期,不代表论文的发表时间)
共2页
377-378