SARS-CoV-2-induced lung pathology:AHR as a candidate therapeutic target
The aryl hydrocarbon receptor(AHR)is activated by multiple viruses to evade the host immune response,a strategy exploited in pre-clinical models to limit the replication of Zika and Influenza A.In a recent study,Liu et al.report that AHR drives the hypersecretion of lung mucins after SARS-CoV-2 infection,suggesting a role for AHR in respiratory failure and highlighting its potential therapeutic value.
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2021-03-05(万方平台首次上网日期,不代表论文的发表时间)
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