Secret(ory) revealed: the long-awaited structures of secretory IgA
Secretory IgA (SIgA) is a specialized form of antibody present at high concentrations in mucosal secretions, where it acts as the first line of defense of the immune system.In a recent paper published in Cell Research, Wang et al.present cryo-EM structures revealing the architecture of SIgA and its interactions with SpsA, a pneumococcal adhesin that piggybacks on SIgA to facilitate gut colonization and host cell invasion by Streptococcus pneumoniae.
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2020-08-14(万方平台首次上网日期,不代表论文的发表时间)
共2页
558-559