A β-galactosidase kiss of death for senescent cells
In a recent paper published in Cell Research, Cai et al.report development of the prodrug senescence-specific killing compound 1 (SSK1), which specifically clears SA-β-galactosidase-positive senescent cells both in vitro and in vivo.By activation of the p38 MAPK pathway and induction of cellular apoptosis, SSK1 functions broadly to attenuate chronic inflammation and improve physiological function.
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2020-08-14(万方平台首次上网日期,不代表论文的发表时间)
共2页
556-557