Mutagenic replication: target for tumor therapy?

摘要：

A study published in Cell by Wojtaszek et al.provides a proof of principle that cancer cells can be sensitized to DNA-damaging chemotherapy by the drug-induced inhibition of mutagenic DNA translesion synthesis,a process that endows tolerance of DNA damage.However,the risk/benefit profile of such a combination therapy should be thoroughly evaluated.

所属期刊栏目：29

在线出版日期：2019-12-11（万方平台首次上网日期，不代表论文的发表时间）

页数：共2页

页码：783-784