Lnc(ing) interferon production and action
Host-virus homeostasis is intricately regulated at multiple steps of both interferon (IFN) induction and IFN action;a recent paper by Zhou et al.has revealed a new feature of this complex regulation.They report the discovery of an IFN-inducible cytoplasmic long non-coding RNA,IncLrrc55-AS,which promotes IRF3 phosphorylation by inactivating the phosphatase PP2A,thus providing a positive feedback loop to IFN induction.
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2019-11-04(万方平台首次上网日期,不代表论文的发表时间)
共2页
690-691