LKB1 restrains dendritic cell function
Three independent recent studies support the notion that liver kinase B1 (LKB1),a key nutrient sensor,controls dendritic cell (DC) function.Selective loss of LKB1 in DCs leads to their increased ability to prime effector T cell responses,but the prevailing effect is the expansion of thymus-derived natural regulatory T cells,creating a dominant immunosuppressive environment.
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2019-07-29(万方平台首次上网日期,不代表论文的发表时间)
共3页
429-431