CasX: a new and small CRISPR gene-editing protein
In a recent paper published in Nature,Liu et al.demonstrate the DNA cleavage characteristics of CasX (a newly identified duaI-RNA-guided DNA targeting nuclease) and establish its capacity for genome editing in Escherichia coli and human cells.Furthermore,they capture structural snapshots of CasX in different states by cryo-EM and establish a model of RNA assembly,DNA targeting and sequential cleavage.
29
2019-06-04(万方平台首次上网日期,不代表论文的发表时间)
共2页
345-346