In vivo ways to unveil off-targets
Base editors enable single nucleotide conversion without causing unwanted indels.Two recent studies reveal that cytosine base editors (CBEs),but not adenine base editors (ABEs),induce unexpected genome-wide off-target mutations,calling for high-fidelity CBEs.
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2019-06-04(万方平台首次上网日期,不代表论文的发表时间)
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339-340