Engineering 3D genome organization
The causal relationship between nuclear position and gene expression remains under intense debate.Qi and colleagues developed the CRISPR-GO system to efficiently reposition any genomic sequence to a specific nuclear compartment and examine its effect on transcription.
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Work in the authors” lab is supported by U.S. Public Health Service Award R01GM035463 from the National Institutes of Health.The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health
2019-03-08(万方平台首次上网日期,不代表论文的发表时间)
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