Circular RNA F-circEA produced from EML4-ALK fusion gene as a novel liquid biopsy biomarker for non-small cell lung cancer
Dear Editor,Non-small cell lung cancer (NSCLC) accounts for over 75% cases of lung cancer,the leading cause of cancer deaths in the world.Most NSCLC patients are diagnosed at an advanced stage due to the inadequate screening program and late onset of clinical symptoms,leading to poor prognosis.1 Discovery of accurate and sensitive biomarkers is in urgent need.Recently,circular RNAs (circRNAs) are emerging as a novel biomarker because of their conservation,abundance,cell type-specific and tissue-specific expression,and their roles in disease progression.2,3
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the National Key R&D Program of China2017YFA0504304 and 2016YFA0502204 to Y.P.;National Natural Science Foundation of China81772960 and 81572739 to Y.P.
2018-09-28(万方平台首次上网日期,不代表论文的发表时间)
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693-695