Human embryonic stem cells contribute to embryonic and extraembryonic lineages in mouse embryos upon inhibition of apoptosis

摘要：

Dear Editor,Recently,interspecies chimera formation has been established in rodents by injection of rat pluripotent stem cells (PSCs) into mouse early embryos,and such a system provides an in vivo assay to test the developmental potential of human PSCs (hPSCs) ”1”.In addition,the interspecies chimeras formed between hPSCs and large animal embryos would open new avenues to generate human tissues and organs for regenerative medicine ”2”.

所属期刊栏目：28

资助基金：We appreciate the discussion of all members in Dr Hu”s lab,Dr Li”s lab and Dr Zhou”s lab.This work was supported by the National Natural Science Foundation of China31422038 and 31471395;the National Basic Research Program of China2014CB964800;the CAS Strategic Priority Research Program QYZDY-SSW-SMC002,QYZDB-SSW-SMC022.We thank Shiwen Li,Xili Zhu,and Qing Meng from the State Key Laboratory of Stem Cell and Reproductive Biology for their technical support

在线出版日期：2018-03-06（万方平台首次上网日期，不代表论文的发表时间）

页数：共4页

页码：126-129