Threading an elephant through the eye of a needle: Where are platelets made?
There has been a long-standing controversy of whether megakaryocytes release platelets in the marrow or travel to the lungs and release platelets there.Using two-photon electron microscopy and orthotopic lung transplantation,Lefran(c)ais et al.now document that platelet release occurs physiologically in the lungs of mice from extrapulmonary megakaryocytes and that this release accounts for ~50% of total platelet production.
lung transplantation、electron microscopy
27
R65;R3
2017-10-16(万方平台首次上网日期,不代表论文的发表时间)
共2页
1079-1080