An mRNA-based vaccine strategy against Zika
Infections with Zika virus are strongly associated with complications such as congenital microcephaly and can trigger Guillain-Barré syndrome in humans,highlighting the urgent need for a safe,efficacious vaccine as a preventative countermeasure.In a recent paper published in Cell,Richner etal.generated a lipid nanoparticle encapsulated modified mRNA vaccine encoding the prM and E genes from Zika virus,which showed protection and sterilizing immunity in immunocompetent mice.
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2017-10-16(万方平台首次上网日期,不代表论文的发表时间)
共2页
1077-1078