Spontaneous DNA damage propels tumorigenicity
High levels of endogenously generated DNA damage drive oncogenesis,sustain malignant progression and increase therapy resistance.In a paper recently published in Cell Research,Liu and colleagues added additional insights into this topic by uncovering a novel intrinsic source of double-strand breaks that fosters the aggressiveness and stemness of malignant cells.
malignant progression、DNA damage
27
R73
2017-07-18(万方平台首次上网日期,不代表论文的发表时间)
共2页
720-721