Hitting the right button: MAVS-mediated defense against HAV infection
Studying the immune response against infection with hepatitis viruses is hampered by the lack of suitable preclinical model systems.A recent publication in Science identifies the cytosolic adapter molecule MAVS as being responsible for species restriction of infection with hepatitis A virus as well as linking cytosolic immune sensing in infected hepatocytes with innate effector functions and protective adaptive immunity.
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2017-02-27(万方平台首次上网日期,不代表论文的发表时间)
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