Artemisinin derivatives prevent obesity by inducing browning of WAT and enhancing BAT function
Dear Editor,Obesity and its related disorders have become a global pandemic ”1”.Obesity leads to multiple chronic morbidities such as fatty liver,type 2 diabetes and cardiovascular diseases,and even increases the risk of several cancers.Five drugs have been approved by the Food and Drug Administration (FDA) for long-term weight management;however,there is still a long way to go before achieving satisfactory clinical outcome due to modest efficacy and unfavorable side effects ”2”.Current anti-obesity medications focus mainly on restricting energy intake either by decreasing fat absorption or by suppressing appetite.
26
This work was supported by the National Key Basic Research Project 2013CB530601 and the National Natural Science Foundation of China the State Key Program,31030048 and 81390350 to Qi-qun Tang.The department is supported by 985 Project 985 Ⅲ-YFX0302.
2016-11-23(万方平台首次上网日期,不代表论文的发表时间)
1169-1172