Ever HRD a ubiquitin-gated channel?
Elimination of misfolded proteins of the endoplasmic reticulum (ER) requires their retrotranslocation from the ER to the cytosol via membranebound ubiquitin ligase complexes.Baldridge and Rapoport now reconstitute a key step of retrotranslocation,demonstrating a protein conduit gated by ubiquitination.
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2016-11-23(万方平台首次上网日期,不代表论文的发表时间)
1075-1076